Hiroyuki SASAKI

佐々木裕之(Hiroyuki Sasaki)

Kyushu University Senior Vice President
Dean of the Institute for Advanced Study


Specialized Fields :
Molecular Biology, Genetics

Academic Background

March 1982

Bachelor of Medicine, School of Medicine, Kyushu University

March 1987

M.D.,Ph.D., Graduate School of Medical Science, Kyushu University

Occupation Background

May 1987

Research Associate of Institute of Genetic Information, Kyushu University

April 1990

British AFRC council fellow

November 1992

Welcome/CRC Researcher of University of Cambridge

April 1993

Associate Professor of Institute of Genetic Information, Kyushu University

December 1998

Professor of Department of Integrated Genetics, National Institute of Genetics

April 2004

Professor of Department of Integrated Genetics, National Institute of Genetics, Research Organization of Information and Systems

January 2010

Professor of Department of Molecular and Structural Biology, Medical Institute of Bioregulation, Kyushu University

May 2010

Distinguished Professor of Kyushu University

April 2012

Dean of Medical Institute of Bioregulation, Kyushu University

October 2014

Senior Vice President of Kyushu University

April 2018

Dean of Institute for Advanced Study, Kyushu University

April 2019

R&D Area Advisor of Japan Agency for Medical Research and Development AMED-CREST/PRIME 「The early life stages」

Academic Awards・Awards

F.Y.2009

The Japan Society of Human Genetics Award

F.Y.2012

The Genetic Society of Japan The Kihara Prize

F.Y.2015

The Medal with Purple Ribbon

F.Y.2018

The Uehara Prize

Publication List

  • Tucci, V., Isles, A., Kelsey, G., Ferguson-Smith, A.C. & The Erice Imprinting Group. Genomic imprinting and physiological processes in mammals. Cell 176, 952-965 (2019).
  • Yamashiro, C., Sasaki, K., Yabuta, Y., Kojima, Y., Nakamura, T., Okamoto, I., Yokobayashi, S., Murase, Y., Ishikura, I., Shirane, K., Sasaki, H., Yamamoto, T. & Saitou, M. Generation of human oogonia from induced pluripotent stem cells in vitro. Science 362, 356-360 (2018).
  • Stunnenberg, H.G., The International Human Epigenome Consortium & Hirst, M. The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery. Cell 167, 1145-1149 (2016).
  • Watanabe, T., Tomizawa, S., Mitsuya, K., Totoki, Y., Yamamoto, Y., Kuramochi-Miyagawa, S., Iida, N., Hoki, Y., Murphy, P.J., Toyoda, A., Gotoh, K., Hiura, H., Arima, T., Fujiyama, A., Sado, T., Shibata, T., Nakano, T., Lin, H., Ichiyanagi, K., Soloway, P.D. & Sasaki, H. Role for piRNAs and non-coding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science 332, 848-852 (2011).
  • Sasaki, H. & Matsui, Y. Epigenetic events in mammalian germ-cell development: reprogramming and beyond. Nat. Rev. Genet. 9, 129-140 (2008).
  • Watanabe, T., Totoki, Y., Toyoda, A., Kaneda, M., Kuramochi-Miyagawa, S., Obata, Y., Chiba, H., Kohara, Y., Kono, T., Nakano, T., Surani, M.A., Sakaki, Y. & Sasaki, H. Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes. Nature 453, 539-543 (2008).
  • Kaneda, M., Okano, M., Hata, K., Sado, T., Tsujimoto, N., Li, E. & Sasaki, H. Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature 429, 900-903 (2004).
  • Ferguson-Smith, A.C., Sasaki, H., Cattanach, B.M. & Surani, M.A. Parental-origin-specific epigenetic modification of the mouse H19 gene. Nature 362, 751-755 (1993).
  • Sasaki, H., Sakaki, Y., Takagi, Y., Sahashi, I., Takahashi, A., Shinoda, T., Isobe, T., Matsuo, H., Goto, I. & Kuroiwa, Y. Presymptomatic diagnosis of heterozygosity for familial amyloidotic polyneuropathy by recombinant DNA techniques. Lancet 325, 100-100 (1985).